Chameleon
Manufacturer – sptlabtech
Description: The chameleon is a next-generation, automated sample preparation instrument for cryo-Electron Microscopy (cryo-EM). It is a blot-free, pico-liter dispenser and high-speed plunge-freezer that uses proprietary self-wicking grids to produce consistent, high-quality frozen-hydrated samples. It is a fully automated, blot-free, pico-liter cryo-EM sample vitrification instrument that rapidly freezes biological samples on self-wicking grids to create high-quality frozen grids for structural biology.
Technical Specifications:
Minimum sample volume: 5 µL
Sample block temperature control: 4°C to 37°C
Minimum dispense volume: 6 nL
Weight : 300kg
Standard dispense-to-plunge time: 101 msec
Dimensions (W x D x H): 916 mm x 708 mm x 1687 mm
Fastest dispense-to-plunge time: 54 msec
Key Features:
• Blot-Free Technology
• High-Speed Plunging
• Pico-Liter Dispensing
• Full Automation
• On-board Optical Screening
Applications:The chameleon’s concise applications are in Structural Biology, specifically automating the cryo-EM sample preparation of macromolecules. Its blot-free, high-speed vitrification helps overcome challenges like preferred particle orientation and denaturation for high-resolution analysis.
Accessory: Quantifoil – self-wicking cryo-EM support grid.