ISQ™ EM Single Quadrupole Mass Spectrometer

Manufacturer – Thermo Fisher Scientific

Description: The Thermo Scientific™ ISQ™ EM Single Quadrupole Mass Spectrometer is a robust and flexible instrument designed for seamless integration with LC systems, delivering reliable, routine LC-MS performance with an extended mass range. It supports interchangeable HESI and APCI probes, enabling analysis of a broad spectrum of analytes from small molecules to larger compounds.

Technical Specifications:
Mass range: 10–2000 m/z (unit mass resolution)
Scan rate: Up to 20,000 Da/s
Polarity switching: ~25 ms (HESI mode)
Ionization source: Atmospheric Pressure Ionization (API) with interchangeable HESI and APCI probes
Flow rate compatibility: Up to ~2 mL/min
Gas requirement: Nitrogen ≥ 99% purity, ~30 L/min at 90–110 psig
Dimensions / weight: 52 cm (H) × 42 cm (W) × 91 cm (D); ~71 kg (≈157 lb)
Key Features:
• Extended mass range for detection of small and large molecules.
• Interchangeable HESI and APCI probes for flexible ionization options.
• Durable API source and vacuum interlock for high reliability and uptime.
• Built-in calibration standard for automated tuning and accuracy.
• Ultra-fast scanning enables simultaneous detection of multiple ions.
• Software-assisted method setup for optimized performance.
• Full integration with Thermo Scientific™ Chromeleon™ CDS for streamlined control and data management.
Application: Ideal for routine LC-MS analysis of diverse analytes from small organic molecules to larger species in pharmaceutical, food, environmental, and industrial laboratories.
Catalogs:
ISQEM-ESI – LC-MS, HESI source
ISQEM-ESI-APCI – LC-MS, dual HESI/APCI source

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