Orbitrap™ IQ-X™ Tribrid™ Mass Spectrometer
Manufacturer – Thermo Fisher Scientific
Description: Q Exactive UHMR system enables ultra-high mass range analysis (up to ~m/z 80,000) for intact protein complexes and large biomolecular assemblies. It combines high-performance quadrupole precursor selection, in-source trapping, a HCD cell, and a high-resolution Orbitrap analyzer for sensitive detection in the high-mass regime.
Technical Specifications:
Mass range: m/z 350 – ~80,000
Quadrupole isolation range: up to m/z 25,000Resolution: up to 200,000 FWHM at m/z 400
Scan rate: up to 12 Hz (at 12,500 resolution)
Mass accuracy: Internal < 1 ppm RMS; External < 3 ppm RMS
Dynamic range: > 5,000:1 (single scan)
Key Features:
• In-source trapping (IST) for efficient high-mass ion transmission and control.
• Advanced Quadrupole Technology (AQT) for high-mass precursor isolation (up to m/z 25,000).
• Optimized RF ion guides for improved transmission and sensitivity.
• Supports native and top-down MS for intact complex and membrane protein analysis.
Applications: Ideal for native MS of large protein complexes, membrane proteins, and biotherapeutic assemblies.
Catalog Numbers:
FSN05-10001 – Orbitrap IQ-X Tribrid MS IC
SOT01-10000 – 1M Resolution
UVPD1-10000 – UV Photodissociation