Technical Specifications:
Mass Range: 50 to 2000 m/z (standard); up to 8000 m/z (High Mass Range mode)
Resolution: Up to 500,000 FWHM at m/z 200
Scan Rate: Up to 40 Hz for MSⁿ
Mass Accuracy: <3 ppm RMS (external calibration); <1 ppm RMS (internal calibration)
Dynamic Range: >5000 within a single spectrum
Polarity Switching: <1.1 seconds per full cycle
Weight: 180 kg (400 lb)
Dimensions: 77 x 127 x 70 cm
Key Features:
• QR5 Segmented Quadrupole Mass Filter: Enhances precursor selectivity and sensitivity with narrow isolation widths.
• Ultra-High-Field Orbitrap Mass Analyzer: Achieves high resolution and fast MSⁿ acquisition rates.
• Dual-Pressure Linear Ion Trap: Supports multiple fragmentation techniques including CID, HCD, ETD, and UVPD.
• Real-Time Search (RTS): Enables on-the-fly peptide identification for improved quantification.
• Proton Transfer Charge Reduction (PTCR): Simplifies complex top-down spectra for better interpretation.
• High Mass Range MSⁿ (HMRⁿ): Facilitates analysis of native protein complexes up to m/z 8000.
• EASY-IC Ion Source: Provides real-time internal calibration for sub-1 ppm mass accuracy.
Applications: Ideal for proteomics, top-down analysis, TMT quantification, native MS, and structural characterization of complex biomolecules.