LTQ XL Linear Ion Trap Mass Spectrometer
Manufacturer – Thermo Fisher Scientific
Description: LTQ XL linear ion trap mass spectrometer delivers high‑sensitivity full‑scan MS along with in‑depth MSⁿ capabilities and is an affordable general‑purpose MS for proteomics, metabolite, and unknown‑analysis workflows. It supports multiple dissociation techniques (CID, PQD, and optionally ETD), fast polarity switching, and data‑dependent acquisition to enable structural characterization of complex molecules.
Technical Specifications:
Mass range: m/z 15‑200; m/z 50‑2000; m/z 200‑4000
Scan power: MSⁿ for n = 1 through 10
Polarity switching: < 100 ms between positive and negative
Resolution (FWHM): 0.15; 0.3; 0.45; 0.7; 3.0
Sensitivity: Using HESI — loop injection of 2 µL of 125 fg/µL reserpine (250 fg total) yields a minimum S/N of 100:1
Power requirements: 230 V, 15 A, 50/60 Hz
Weight: ~120 kg
Key Features:
• Unparalleled sensitivity and unmatched MSⁿ spectral quality
• Pulsed Q dissociation (PQD) to generate more fragments and extend the low‑mass range
• High‑resolution isolation (HRI) enabling isolation of isobaric mass peaks for cleaner MSⁿ spectra
• Ultra‑fast polarity switching for high sensitivity analysis of unknowns
• Automated data‑dependent neutral loss experiments for post‑translational modification (PTM) and biotransformation analyses
• Excellent charge‑state determination via Ultra ZoomScan™ mode
• Broad ionisation source compatibility (ESI, HESI, APCI, APPI) supporting varied liquid flows and analyte types
Applications: Ideal for protein identification & quantitative differential expression, biomarker studies & PTM identification, metabolite identification & quantification, tissue imaging, and high‑speed LC methods.
Catalog:
IQLAAEGAAVFACZMAIK – LTQ XL Linear Ion Trap MS
